Multi-marker modeling with kidney-related biomarkers and cardiovascular outcomes

In his talk, practical examples of confirmatory and exploratory factor analysis will be presented along with several research findings in nephrology. The first example is to integrate four biomarkers related to kidney function into a single latent factor in the general population of South Tyrol (N=1,300), and examines the association between the latent factor and binary outcome of cardiovascular disease risk scores (Fujii R, et al. PLoS One 2023). The second example included our similar attempt in the UK Biobank participants (N=360,000), and examined the associations between latent factors and all-cause and cause-specific mortality using time-event analysis (Selected as an oral presentation at the European Renal Association (ERA conference 23, Milano). In this talk, he will briefly explain statistical methods to evaluate the performance of predictors such as discrimination and prediction ability

Where: Aula De Lillo, Bulding U7-2nd Floor, University of Milano-Bicocca

Time: May 12 2023, 2:30 PM - 3:30 PM

Seminar SpeakerRyosuke Fujii, PhD - Institute for Biomedicine, Eurac Research, Italy - Department of Preventive Medical Sciences, Fujita Health University School of Medical Sciences, Japan

About the Speaker: Dr. Fujii is a Senior Researcher at the Institute for Biomedicine, Eurac Research (Italy) and an Assistant Professor at the Department of Preventive Medical Sciences, Fujita Health University School of Medical Sciences (Japan). His research interest at an early-career stage was epidemiological relationships among biomarkers, nutritional intake, genetics, epigenetics, and chronic diseases in Japanese populations. The current primary research theme is genetic epidemiology for population-based studies of chronic disease, particularly cardiovascular disease, and chronic kidney disease. The latest publications are related to genome-wide polygenic risk score for hypertension in a Japanese population (Fujii R, et al. Circ Genom Precis Med 2022) and mendelian randomization between obesity/obese and kidney function (Fujii R & Pattaro C. Cardiovasc Res 2022)

Zoom:  https:/

Meeting ID :  651 0002 8770

Password: 490973

Note: The seminar flyer, slides, and recording, when possible, will be available on, under the events section. 

Important: Late minute changes, technical problems with zoom, etc,  will be immediately posted in our homepage  (under the "eventi e news" page) to eventually reschedule the seminar

Host:  Dr. Rino Bellocco and  Edoardo Ratti

For more info: locandina